Disease

"Mr. Elcock, student of anatomy, slightly punctured his finger in opening the body of a hospital patient about twelve o'clock at noon, and in the evening of the same day, finding the wound painful, showed it to Sir Astley Cooper after his surgical lecture. During the night the pain increased to extremity, and symptoms of high constitutional irritation presented themselves on the ensuing morning. No trace of inflammation was apparent beyond a slight redness of the spot at which the wound had been inflicted, which was a mere puncture. In the evening he was visited by Dr. Babington, in conjunction with Dr. Haighton and Sir Astley Cooper; still no local change was to be discovered, but the nervous system was agitated in a most violent and alarming degree, the symptoms nearly resembling the universal excitation of  hydrophobia, and in this state he expired within the period of forty-eight hours from the injury".

From  : PRACTICE OF INTERMENT IN TOWNS EDWIN CHADWICK, (1843)